“Paper Machine” for Molecular Diagnostics
نویسندگان
چکیده
منابع مشابه
"Paper Machine" for Molecular Diagnostics.
Clinical tests based on primer-initiated amplification of specific nucleic acid sequences achieve high levels of sensitivity and specificity. Despite these desirable characteristics, these tests have not reached their full potential because their complexity and expense limit their usefulness to centralized laboratories. This paper describes a device that integrates sample preparation and loop-m...
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The cost of the device, as shown in Figure 1, was estimated using low-volume pricing for all materials and reagents (Table S1). Once scaled-up for high-volume manufacturing, bulk discounts would further decrease the total cost. The transition from 25 µL LAMP reactions in tubes, to 10 µL reactions run in FTA paper, required optimization of the reaction conditions. Here, we investigated two diffe...
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ژورنال
عنوان ژورنال: Analytical Chemistry
سال: 2015
ISSN: 0003-2700,1520-6882
DOI: 10.1021/acs.analchem.5b00411